ARG22834

anti-IFN gamma antibody [CC302]

anti-IFN gamma antibody [CC302] for ELISA,Flow cytometry and Human,Bovine,Dolphin,Dog,Ferret,Goat,Horse,Pig,Rabbit,Sheep

Overview

Product Description Mouse Monoclonal antibody [CC302] recognizes IFN gamma
Tested Reactivity Hu, Bov, Dlph, Dog, Frt, Goat, Hrs, Pig, Rb, Sheep
Tested Application ELISA, FACS
Host Mouse
Clonality Monoclonal
Clone CC302
Isotype IgG1
Target Name IFN gamma
Antigen Species Bovine
Conjugation Un-conjugated
Alternate Names IFN-gamma; Interferon gamma; Immune interferon; IFG; IFI

Application Instructions

Application Suggestion
Tested Application Dilution
ELISAAssay-dependent
FACS1:10 - 1:100
Application Note FACS: Membrane permeabilization is required for this application. Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl.
ELISA: Biotinylated mouse anti bovine IFN gamma , clone CC302, may be used as the detection reagent in a sandwich ELISA.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein G.
Buffer PBS and 0.09% Sodium azide
Preservative 0.09% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 3458 Human IFNG

Swiss-port # P01579 Human Interferon gamma

Gene Symbol IFNG
Gene Full Name interferon, gamma
Background This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of the both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial inflections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Sep 2015]
Function Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. [UniProt]
Highlight Related products:
IFN gamma antibodies; IFN gamma ELISA Kits; IFN gamma Duos / Panels; IFN gamma recombinant proteins; Anti-Mouse IgG secondary antibodies;
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Inflammatory Cytokines
Calculated MW 19 kDa
PTM Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161.