ARG44380
anti-ICMT antibody
anti-ICMT antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ICMT |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ICMT |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 175-284 of human ICMT |
| Conjugation | Un-conjugated |
| Alternate Names | ICMT; Isoprenylcysteine Carboxyl Methyltransferase; PCCMT; PPMT; Protein-S-Isoprenylcysteine O-Methyltransferase; HSTE14; Prenylated Protein Carboxyl Methyltransferase; Prenylcysteine Carboxyl Methyltransferase; EC 2.1.1.100; Isoprenylcysteine Carboxylmethyltransferase; MSTP098; MST098; PcCMT; PCMT |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% sodium azide and 50% Glycerol. |
| Preservative | 0.02% sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O60725 Human Protein-S-isoprenylcysteine O-methyltransferase Swiss-port # Q9EQK7 Mouse Protein-S-isoprenylcysteine O-methyltransferase |
|---|---|
| Gene Symbol | ICMT |
| Gene Full Name | Isoprenylcysteine Carboxyl Methyltransferase |
| Background | This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined. |
| Function | Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues. |
| Cellular Localization | Endoplasmic reticulum, Membrane |
| Calculated MW | 32 kDa |
Images (5) Click the Picture to Zoom In
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ARG44380 anti-ICMT antibody WB image
Western blot: K562, HeLa and THP-1 stained with ARG44380 anti-ICMT antibody at 1:1000 dilution.
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ARG44380 anti-ICMT antibody IHC-P image
Immunohistochemistry: Rat heart stained with ARG44380 anti-ICMT antibody at 1:200 dilution.
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ARG44380 anti-ICMT antibody IHC-P image
Immunohistochemistry: Rat testis stained with ARG44380 anti-ICMT antibody at 1:200 dilution.
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ARG44380 anti-ICMT antibody WB image
Western blot: Rat testis stained with ARG44380 anti-ICMT antibody at 1:1000 dilution.
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ARG44380 anti-ICMT antibody WB image
Western blot: Mouse testis and Mouse lung stained with ARG44380 anti-ICMT antibody at 1:1000 dilution.
