ARG44585
anti-Hsp 70 antibody
anti-Hsp 70 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Monoclonal antibody recognizes Hsp 70 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Target Name | Hsp 70 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to internal region of human Hsp 70. |
| Conjugation | Un-conjugated |
| Alternate Names | HSPA1A; Heat Shock Protein Family A (Hsp70) Member 1A; HSP70-1; HSPA1; Heat Shock 70 KDa Protein 1A; Heat Shock 70kDa Protein 1A; Heat Shock 70 KDa Protein 1; Heat Shock 70kD Protein 1A; HSP70.1; HSP72; Epididymis Secretory Sperm Binding Protein; DnaK-Type Molecular Chaperone HSP70-1; Epididymis Secretory Protein Li 103; Heat Shock 70 KDa Protein 1A/1B; Heat Shock 70 KDa Protein 1/2; Heat Shock 70 KDa Protein 1B; Heat Shock 70 KDa Protein 2; Heat Shock-Induced Protein; HSP70-1/HSP70-2; HSP70.1/HSP70.2; HEL-S-103; HSP70-1A; HSP70-2; HSP70.2 ; HSP70I; HSP70; HSX70 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity Purified |
| Buffer | 50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 40% Glycerol and 0.05% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | HSPA1A |
| Gene Full Name | Heat Shock Protein Family A (Hsp70) Member 1A |
| Background | This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008] |
| Function | Involved in the clearance of misfolded PRDM1/Blimp-1 proteins. Sequesters them in the cytoplasm and promotes their association with SYNV1/HRD1, leading to proteasomal degradation. [UniProt] |
| Cellular Localization | Cytoplasm, Cytoskeleton, Nucleus, Secreted. [UniProt] |
| Calculated MW | 70 kDa |
| PTM | Acetylation, Methylation, Phosphoprotein. [UniProt] |
Images (5) Click the Picture to Zoom In
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ARG44585 anti-Hsp 70 antibody IHC-P image
Immunohistochemistry: Human tonsil stained with ARG44585 anti-Hsp 70 antibody at dilution.
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ARG44585 anti-Hsp 70 antibody ICC/IF image
Immunofluorescence: Hsp70 stained with ARG44585 anti-Hsp 70 antibody.
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ARG44585 anti-Hsp 70 antibody WB image
Western blot: K562 stained with ARG44585 anti-Hsp 70 antibody.
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ARG44585 anti-Hsp 70 antibody WB image
Western blot: Rat Brain stained with ARG44585 anti-Hsp 70 antibody.
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ARG44585 anti-Hsp 70 antibody WB image
Western blot: 3T3 stained with ARG44585 anti-Hsp 70 antibody.
