ARG55103
anti-Hexokinase 2 antibody
anti-Hexokinase 2 antibody for Western blot and Human,Monkey
Cancer antibody; Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody
Overview
| Product Description | Mouse Monoclonal antibody recognizes Hexokinase 2 |
|---|---|
| Tested Reactivity | Hu, Mk |
| Tested Application | WB |
| Specificity | This antibody detects endogenous levels of Hexokinase II and does not cross-react with related proteins. |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | Hexokinase 2 |
| Antigen Species | Human |
| Immunogen | Purified recombinant Human Hexokinase II protein fragments expressed in E.coli. |
| Conjugation | Un-conjugated |
| Alternate Names | Muscle form hexokinase; HK II; Hexokinase-2; Hexokinase type II; EC 2.7.1.1; HXK2; HKII |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Purification | Affinity purification with immunogen. |
|---|---|
| Buffer | PBS (pH 7.4), 0.03% Proclin 300 and 50% Glycerol |
| Preservative | 0.03% Proclin 300 |
| Stabilizer | 50% Glycerol |
| Concentration | 9.050000000000001 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | HK2 |
| Gene Full Name | hexokinase 2 |
| Background | Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009] |
| Cellular Localization | Mitochondrion outer membrane. |
| Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody |
| Calculated MW | 102 kDa |
Images (1) Click the Picture to Zoom In
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ARG55103 anti-Hexokinase 2 antibody WB image
Western blot: COS7 cell lysate stained with ARG55103 anti-Hexokinase 2 antibody at 1:1000 dilution.
