ARG44612

anti-HVEM / TR2 antibody [CW10] (PE)

anti-HVEM / TR2 antibody [CW10] (PE) for Flow cytometry and Human

Overview

Product Description PE-conjugated Mouse Monoclonal antibody recognizes HVEM / TR2
Tested Reactivity Hu
Tested Application FACS
Host Mouse
Clonality Monoclonal
Clone CW10
Isotype IgG1 kappa
Target Name HVEM / TR2
Antigen Species Human
Conjugation PE
Alternate Names TNFRSF14; TNF Receptor Superfamily Member 14; HVEM; HVEA; TR2; LIGHTR; CD270; ATAR; Tumor Necrosis Factor Receptor Superfamily, Member 14 (Herpesvirus Entry Mediator); Tumor Necrosis Factor Receptor Superfamily Member 14; Herpes Virus Entry Mediator A; Tumor Necrosis Factor Receptor Superfamily, Member 14; Tumor Necrosis Factor Receptor-Like Gene2; Tumor Necrosis Factor Receptor-Like 2; Herpesvirus Entry Mediator A; Herpesvirus Entry Mediator; CD40-Like Protein; CD270 Antigen; HveA

Application Instructions

Application Suggestion
Tested Application Dilution
FACS10 µl / 100 µl or 10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified antibody is conjugated with R-phycoerythrin (PE), and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Buffer PBS (pH 7.4) and 15 mM Sodium azide
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 8764 Human TNFRSF14

Swiss-port # Q92956 Human Tumor necrosis factor receptor superfamily member 14

Gene Symbol TNFRSF14
Gene Full Name tumor necrosis factor receptor superfamily, member 14
Background This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Function In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells. [UniProt]
Cellular Localization Cell membrane, Membrane. [UniProt]
Calculated MW 30 kDa
PTM Disulfide bond, Glycoprotein, Phosphoprotein. [UniProt]

Images (1) Click the Picture to Zoom In

  • ARG44612 anti-HVEM / TR2 antibody [CW10] (PE) FACS image

    Flow Cytometry: SK-MEL-30 stained with ARG44612 anti-HVEM / TR2 antibody [CW10] (PE) at 10 μl/ 100 μl dilution.