ARG63992
anti-HTR1B / Serotonin Receptor 1B antibody
anti-HTR1B / Serotonin Receptor 1B antibody for Western blot and Human,Mouse
Metabolism antibody; Neuroscience antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes HTR1B / Serotonin Receptor 1B |
|---|---|
| Tested Reactivity | Hu, Ms |
| Predict Reactivity | Cat, Rat, Cow, Dog, Pig |
| Tested Application | WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | HTR1B / Serotonin Receptor 1B |
| Antigen Species | Human |
| Immunogen | C-SNEDFKQAFHK |
| Conjugation | Un-conjugated |
| Alternate Names | 5-hydroxytryptamine receptor 1B; HTR1D2; S12; 5-HT-1D-beta; Serotonin 1D beta receptor; Serotonin receptor 1B; HTR1DB; 5-HT1B; 5-HT-1B; 5-HT1DB |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.[supplied by OMIM, Oct 2009] |
| Research Area | Metabolism antibody; Neuroscience antibody |
| Calculated MW | 44 kDa |
| PTM | Phosphorylated. Desensitization of the receptor may be mediated by its phosphorylation. Palmitoylated. |
Images (2) Click the Picture to Zoom In
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ARG63992 anti-HTR1B / Serotonin Receptor 1B antibody WB image
Western blot: Human Brain lysate (35 µg protein in RIPA buffer) stained with ARG63992 anti-HTR1B / Serotonin Receptor 1B antibody at 2 µg/ml dilution.
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ARG63992 anti-HTR1B / Serotonin Receptor 1B antibody WB image
Western blot: 35 µg of Human cerebellum (A) and Mouse spinal cord (B) lysates (in RIPA buffer) stained with ARG63992 anti-HTR1B / Serotonin Receptor 1B antibody at 1 µg/ml dilution and incubated at RT for 1 hour.
