ARG44780
anti-HSPC142 antibody
anti-HSPC142 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
Product Description | Mouse Monoclonal antibody recognizes HSPC142 |
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Tested Reactivity | Hu |
Tested Application | IHC-P |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG2a |
Target Name | HSPC142 |
Antigen Species | Human |
Epitope | QQKTELPVTE NVQTIPPPYV VRTILVYSRP PCQPQFSLTE PMKKMFQCPY FFFDVVYIHN GTEEKEEEMS WKDMFAFMGS LDTKGTSYKY EVALAGPALE LHNCMAKLLA HPLQRPCQSH ASYSLLEEED |
Conjugation | Un-conjugated |
Alternate Names | BABAM1; BRISC And BRCA1 A Complex Member 1; MERIT40; NBA1; C19orf62; HSPC142; Mediator Of RAP80 Interactions And Targeting Subunit Of 40 KDa; New Component Of The BRCA1-A Complex; BRISC And BRCA1-A Complex Member 1; FLJ20571; Mediator Of Rap80 Interactions And Targeting 40 KDa; Mediator Of Rap80 Interactions And Targeting 40 KD; New Component Of The BRCAA1 A Complex; New Component Of The BRCA1 A Complex; Chromosome 19 Open Reading Frame 62; BRCA1-A Complex Subunit MERIT40 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Protein A purification |
Buffer | PBS with 0.09% sodium azide |
Preservative | 0.09% sodium azide |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q9NWV8 Human BRISC and BRCA1-A complex member 1 |
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Gene Symbol | BABAM1 |
Gene Full Name | BRISC And BRCA1 A Complex Member 1 |
Background | Involved in several processes, including mitotic G2 DNA damage checkpoint signaling; positive regulation of DNA repair; and protein K63-linked deubiquitination. Located in cytosol and nuclear body. Part of BRCA1-A complex and BRISC complex. [provided by Alliance of Genome Resources, Apr 2022] |
Function | Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination. [Uniprot] |
Cellular Localization | Cytoplasm, Nucleus. [Uniprot] |
PTM | Acetylation, Phosphoprotein. [Uniprot] |
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