ARG44676
anti-HSPA2 antibody
anti-HSPA2 antibody for Immunoprecipitation and Human,Mouse
Overview
| Product Description | Mouse Monoclonal antibody recognizes HSPA2 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IP |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Target Name | HSPA2 |
| Antigen Species | Human |
| Conjugation | Un-conjugated |
| Alternate Names | Heat shock 70 kDa protein 2; Heat shock-related 70 kDa protein 2; HSP70-2; HSP70-3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P17156 Mouse Heat shock-related 70 kDa protein 2 Swiss-port # P54652 Human Heat shock-related 70 kDa protein 2 |
|---|---|
| Gene Symbol | HSPA2 |
| Gene Full Name | heat shock 70kDa protein 2 |
| Background | Hsp70, one class of stress proteins, is comprised of multiple members, all of which bind ATP in vitro, but are localized within different intracellular compartments. These include: a) the constitutive Hsc70 (or cognate) present within the cytosol/nucleus; b) the highly stress-inducible Hsp70 present within the cytosol/ nucleus/nucleolus; c) the constitutive glucose regulated 78 kDa (or BiP) protein present within the lumen of the endoplasmic reticulum; and d) the glucose regulated 75 kDa protein present within the mitochondria. Hsp70 is typically not expressed in the cell under normal growth conditions, but is expressed at high levels in the cell experiencing stress. Consequently, detection of Hsp70 using an antibody specific for the inducible form is quite useful in ascertaining whether a stress response has occurred in the cell. It should be noted, however, that there is a constitutive level of Hsp70 expression in some cell types such as primates, e.g., human and monkey. Nevertheless increased expression of Hsp70 is observed in such cells following stress. |
| PTM | The N-terminal may be partly blocked. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG44676 anti-HSPA2 antibody IP image
Immunoprecipitation: Mouse Testis lysate immunoprecipitated with 2.5 µg of ARG44676 anti-HSPA2 antibody.
