ARG45247

anti-HSD17B7 antibody

anti-HSD17B7 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat

Overview

Product Description Polyclonal antibody recognizes HSD17B7
Tested Reactivity Hu, Rat
Tested Application FACS, ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name HSD17B7
Antigen Species Human
Immunogen Recombinant protein containing to human HSD17B7.
Conjugation Un-conjugated
Alternate Names HSD17B7; Hydroxysteroid 17-Beta Dehydrogenase 7; SDR37C1; PRAP; 3-Keto-Steroid Reductase/17-Beta-Hydroxysteroid Dehydrogenase 7; Short Chain Dehydrogenase/Reductase Family 37C Member 1; 17-Beta-Hydroxysteroid Dehydrogenase 7; Dihydrotestosterone Oxidoreductase; Estradiol 17-Beta-Dehydrogenase 7; 3-Keto-Steroid Reductase; 17-Beta-HSD 7; Short Chain Dehydrogenase/Reductase Family 37C, Member 1; 17 Beta-Hydroxysteroid Dehydrogenase Type VII; Hydroxysteroid (17-Beta) Dehydrogenase 7; 17beta Hydroxysteroid Dehydrogenase; EC 1.1.1.270; EC 1.1.1.210; EC 1.1.1.62; 17HSD7

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1 - 3 µg/10^6 cells
ICC/IF5 μg/ml
IHC-P2-5 μg/ml
WB0.25-0.5 μg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size 38 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
Stabilizer 4% Trehalose
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 29540 Rat HSD17B7

GeneID: 51478 Human HSD17B7

Swiss-port # P56937 Human 3-keto-steroid reductase

Swiss-port # Q62904 Rat 3-keto-steroid reductase

Gene Symbol HSD17B7
Gene Full Name Hydroxysteroid 17-Beta Dehydrogenase 7
Background HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol (Marijanovic et al., 2003 [PubMed 12829805]).[supplied by OMIM, May 2010]
Function Bifunctional enzyme involved in steroid-hormone metabolism and cholesterol biosynthesis. [UniProt]
Cellular Localization Endoplasmic reticulum ; Membrane. [UniProt]
Calculated MW 38 kDa
PTM Glycoprotein. [UniProt]

Images (5) Click the Picture to Zoom In

  • ARG45247 anti-HSD17B7 antibody IHC-P image

    Immunohistochemistry: Human prostate cancer stained with ARG45247 anti-HSD17B7 antibody at 2 μg/ml dilution.

  • ARG45247 anti-HSD17B7 antibody ICC/IF image

    Immunofluorescence: HepG2 stained with ARG45247 anti-HSD17B7 antibody at 5 ug/ml dilution.

  • ARG45247 anti-HSD17B7 antibody WB image

    Western blot: HL-60 and 293T stained with ARG45247 anti-HSD17B7 antibody at 0.5 μg/ml dilution.

  • ARG45247 anti-HSD17B7 antibody FACS image

    Flow Cytometry: JK stained with ARG45247 anti-HSD17B7 antibody at 1 µg/10^6 cells dilution.

  • ARG45247 anti-HSD17B7 antibody WB image

    Western blot: Rat lung and RH35 stained with ARG45247 anti-HSD17B7 antibody at 0.5 μg/ml dilution.