ARG59735

anti-HSD17B2 antibody

anti-HSD17B2 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes HSD17B2
Tested Reactivity Hu
Tested Application FACS, IHC-P
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name HSD17B2
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide between aa. 265-294 of Human HSD17B2.
Conjugation Un-conjugated
Alternate Names 17-beta-hydroxysteroid dehydrogenase type 2; Short chain dehydrogenase/reductase family 9C member 2; EC 1.1.1.239; HSD17; Estradiol 17-beta-dehydrogenase 2; 20-alpha-HSD; 17-beta-HSD 2; Microsomal 17-beta-hydroxysteroid dehydrogenase; E2DH; SDR9C2; 20 alpha-hydroxysteroid dehydrogenase; EC 1.1.1.62; Testosterone 17-beta-dehydrogenase; EDH17B2

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1:10 - 1:50
IHC-P1:10 - 1:50
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide.
Buffer PBS and 0.09% (W/V) Sodium azide.
Preservative 0.09% (W/V) Sodium azide.
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 3294 Human HSD17B2

Swiss-port # P37059 Human Estradiol 17-beta-dehydrogenase 2

Gene Symbol HSD17B2
Gene Full Name hydroxysteroid (17-beta) dehydrogenase 2
Function Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH. [UniProt]
Cellular Localization Membrane; Single-pass type II membrane protein. [UniProt]
Calculated MW 43 kDa

Images (2) Click the Picture to Zoom In

  • ARG59735 anti-HSD17B2 antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human prostate carcinoma stained with ARG59735 anti-HSD17B2 antibody.

  • ARG59735 anti-HSD17B2 antibody FACS image

    Flow Cytometry: MDA-MB435 cells stained with ARG59735 anti-HSD17B2 antibody (right histogram) or without primary antibody as control (left histogram), followed by incubation with FITC labelled secondary antibody.