ARG56272
anti-HNMT antibody
anti-HNMT antibody for ICC/IF,Immunoprecipitation,Western blot and Human,Mouse
Overview
Product Description | Rabbit Polyclonal antibody recognizes HNMT |
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Tested Reactivity | Hu, Ms |
Tested Application | ICC/IF, IP, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | HNMT |
Antigen Species | Human |
Immunogen | Recombinant protein of Human HNMT |
Conjugation | Un-conjugated |
Alternate Names | HMT; Histamine N-methyltransferase; EC 2.1.1.8; HNMT-S1; HNMT-S2 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
Positive Control | HT-29 |
Properties
Form | Liquid |
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Purification | Affinity purification with immunogen. |
Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
Preservative | 0.02% Sodium azide |
Stabilizer | 50% Glycerol |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | HNMT |
Gene Full Name | histamine N-methyltransferase |
Background | In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008] |
Function | Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine. [UniProt] |
Calculated MW | 33 kDa |
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