ARG59693
anti-HDC / Histidine decarboxylase antibody
anti-HDC / Histidine decarboxylase antibody for Western blot and Human
Overview
| Product Description | Goat Polyclonal antibody recognizes HDC / Histidine decarboxylase |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Cow, Dog, Pig |
| Tested Application | WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | HDC / Histidine decarboxylase |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around the internal region of Human Histidine decarboxylase. (NP_002103.2, C-TVTSQFTTRDDILR) |
| Conjugation | Un-conjugated |
| Alternate Names | HDC; Histidine decarboxylase; EC 4.1.1.22 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| Observed Size | ~ 60 - 70 kDa double band |
Properties
| Form | Liquid |
|---|---|
| Purification | Ammonium sulphate precipitation followed by affinity purification with immunogen. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | HDC |
| Gene Full Name | histidine decarboxylase |
| Background | This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.[provided by RefSeq, Aug 2010] |
| Function | Catalyzes the biosynthesis of histamine from histidine. [UniProt] |
| Calculated MW | 74 kDa |
Images (1) Click the Picture to Zoom In
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ARG59693 anti-HDC / Histidine decarboxylase antibody WB image
Western blot: 35 µg of Human cerebellum lysate (in RIPA buffer) stained with ARG59693 anti-HDC / Histidine decarboxylase antibody at 0.03 µg/ml dilution and incubated at RT for 1 hour.
