ARG20184
anti-HDAC7 antibody
anti-HDAC7 antibody for Immunohistochemistry,Immunoprecipitation,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes HDAC7 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC, IP, WB |
| Specificity | The antibody detects ~105 kDa HDAC7. The antibody does not recognize other members of the HDAC family. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | HDAC7 |
| Immunogen | Synthetic peptide surrounding amino acid 921 of murine HDAC7 |
| Conjugation | Un-conjugated |
| Alternate Names | HD7; Histone deacetylase 7A; EC 3.5.1.98; Histone deacetylase 7; HD7a; HD7A; HDAC7A |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | Mouse small intestine tissue lysate can be use as a positive control. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity Purified Antibody |
| Buffer | PBS (pH 7.2), 30% Glycerol, 0.5% BSA and 0.01% Thimerosal |
| Preservative | 0.01% Thimerosal |
| Stabilizer | 30% Glycerol, 0.5% BSA |
| Concentration | 0.2 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | HDAC7 |
| Gene Full Name | histone deacetylase 7 |
| Background | Human HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription. |
| Calculated MW | 103 kDa |
Images (1) Click the Picture to Zoom In
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ARG20184 anti-HDAC7 antibody WB image
Western Blot: Mouse small intestine tissue lysate stained with anti-HDAC7 antibody (ARG20184).
The antibody detects ~105 kDa HDAC7. Mouse small intestine tissue lysate can be use as a positive control. The antibody does not recognize other members of the HDAC family.
