ARG10126
anti-HBV Core antigen / HBcAg antibody [H3A4]
anti-HBV Core antigen / HBcAg antibody [H3A4] for ELISA,Western blot and HBV
Cancer antibody; Microbiology and Infectious Disease antibody
Overview
| Product Description | Mouse Monoclonal antibody [H3A4] recognizes HBV Core antigen |
|---|---|
| Tested Reactivity | HBV |
| Tested Application | ELISA, WB |
| Specificity | This antibody is specific for HBcAg. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | H3A4 |
| Isotype | IgG2a |
| Target Name | HBV Core antigen / HBcAg |
| Antigen Species | HBV |
| Immunogen | recombinant HBcAg. |
| Conjugation | Un-conjugated |
Application Instructions
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
|---|
Properties
| Form | Liquid |
|---|---|
| Purification | Protein G affinity purified |
| Buffer | PBS (pH 7.4) and 0.1% Sodium azide |
| Preservative | 0.1% Sodium azide |
| Concentration | 1.0-2.0 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | C |
| Gene Full Name | precore protein; external core antigen; HBeAg; p25 |
| Function | Self assembles to form an icosahedral capsid. Most capsid appear to be large particles with a icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins. Entering capsid are transported along microtubules to the nucleus. Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta. Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153. Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm. Immature capsids get stucked in the basket. Capsids encapsulate the pre-genomic RNA and the P protein. Pre-genomic RNA is reverse transcribed into DNA while the capsid is still in the cytoplasm. The capsid can then either be directed to the nucleus, providing more genome for transcription, or bud through the endoplasmic reticulum to provide new virions. Encapsidates hepatitis delta genome. [UniProt] |
| Research Area | Cancer antibody; Microbiology and Infectious Disease antibody |
