ARG67077
anti-HBA1 / Hemoglobin Subunit Alpha 1 antibody [SQab30355]
anti-HBA1 / Hemoglobin Subunit Alpha 1 antibody [SQab30355] for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Recombinant Rabbit Monoclonal antibody [SQab30355] recognizes HBA1 / Hemoglobin Subunit Alpha 1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SQab30355 |
| Isotype | IgG |
| Target Name | HBA1 / Hemoglobin Subunit Alpha 1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide of HBA1 / Hemoglobin Subunit Alpha 1. |
| Conjugation | Un-conjugated |
| Alternate Names | HBA1; Hemoglobin Subunit Alpha 1; HBA-T3; Hemoglobin Subunit Alpha; Hemoglobin, Alpha 1; Hemoglobin Alpha 1 Globin Chain; Hemoglobin Alpha Chain; Alpha-2 Globin Chain; Alpha Globin Chain; Alpha One Globin; Delta Globin; Alpha-Globin; METHBA; ECYT7; HBH |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 40% Glycerol and 0.05% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | HBA1 |
| Gene Full Name | Hemoglobin Subunit Alpha 1 |
| Background | The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. |
| Function | Involved in oxygen transport from the lung to the various peripheral tissues. |
| Calculated MW | 15 kDa |
| PTM | Acetylation, Glycation, Glycoprotein, Phosphoprotein |
Images (1) Click the Picture to Zoom In
-
ARG67077 anti-HBA1 / Hemoglobin Subunit Alpha 1 antibody [SQab30355] IHC-P image
Immunohistochemistry: Human esophagus stained with ARG67077 anti-HBA1 / Hemoglobin Subunit Alpha 1 antibody [SQab30355]
