ARG44599
anti-Galectin 9 antibody [M80] (PE)
anti-Galectin 9 antibody [M80] (PE) for Flow cytometry and Human,Primates
Overview
| Product Description | PE-conjugated Mouse Monoclonal antibody recognizes Galectin 9 |
|---|---|
| Tested Reactivity | Hu, NHuPrm |
| Tested Application | FACS |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | M80 |
| Isotype | IgG1 kappa |
| Target Name | Galectin 9 |
| Antigen Species | Human |
| Immunogen | recombinant M-type splicing variant of human galectin 9 |
| Conjugation | PE |
| Alternate Names | LGALS9; Galectin 9; LGALS9A; Lectin, Galactoside-Binding, Soluble, 9; Tumor Antigen HOM-HD-21; Galectin-9; Ecalectin; Gal-9; Urate Transporter/Channel Protein; HUAT |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified antibody is conjugated with R-phycoerythrin (PE), and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
| Buffer | PBS (pH 7.4) and 15 mM Sodium azide |
| Preservative | 15 mM Sodium azide |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | LGALS9 |
| Gene Full Name | lectin, galactoside-binding, soluble, 9 |
| Background | The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008] |
| Function | Astrocyte derived galectin-9 enhances microglial TNF production. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. May provide the molecular basis for urate flux across cell membranes, allowing urate that is formed during purine metabolism to efflux from cells and serving as an electrogenic transporter that plays an important role in renal and gastrointestinal urate excretion. Highly selective to the anion urate. [UniProt] |
| Cellular Localization | Cytoplasm, Nucleus, Secreted. [UniProt] |
| Calculated MW | 40 kDa |
Images (1) Click the Picture to Zoom In
-
ARG44599 anti-Galectin 9 antibody [M80] (PE) FACS image
Flow Cytometry: Jurkat stained with ARG44599 anti-Galectin 9 antibody [M80] (PE) at 10 μl/ 100 μl dilution.
