ARG43490
anti-Galectin 3BP antibody
anti-Galectin 3BP antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Galectin 3BP |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Galectin 3BP |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to internal region of human nephrin. |
| Conjugation | Un-conjugated |
| Alternate Names | M2BP; Mac-2 BP; Galectin-3-binding protein; Mac-2-binding protein; TANGO10B; Basement membrane autoantigen p105; MAC-2-BP; Tumor-associated antigen 90K; BTBD17B; MAC2BP; gp90; 90K; Lectin galactoside-binding soluble 3-binding protein; CyCAP |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 75 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | LGALS3BP |
| Gene Full Name | lectin, galactoside-binding, soluble, 3 binding protein |
| Background | The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008] |
| Function | Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells. [UniProt] |
| Cellular Localization | Extracellular matrix; Secreted. [UniProt] |
| Calculated MW | 65 kDa |
| PTM | Disulfide bond; Glycoprotein. [UniProt] |
Images (5) Click the Picture to Zoom In
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ARG43490 anti-Galectin 3BP antibody WB image
Western blot: 293T and HepG2 stained with ARG43490 anti-Galectin 3BP antibody at 0.5 μg/ml dilution.
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ARG43490 anti-Galectin 3BP antibody IHC-P image
Immunohistochemistry: Human mammary cancer stained with ARG43490 anti-Galectin 3BP antibody at 2 μg/ml dilution.
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ARG43490 anti-Galectin 3BP antibody WB image
Western blot: Rat brain stained with ARG43490 anti-Galectin 3BP antibody at 0.5 μg/ml dilution.
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ARG43490 anti-Galectin 3BP antibody IHC-P image
Immunohistochemistry: Mouse small intestine stained with ARG43490 anti-Galectin 3BP antibody at 2 μg/ml dilution.
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ARG43490 anti-Galectin 3BP antibody WB image
Western blot: Mouse brain stained with ARG43490 anti-Galectin 3BP antibody at 0.5 μg/ml dilution.
