ARG45199
anti-GSTA4 antibody
anti-GSTA4 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Monkey
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GSTA4 |
|---|---|
| Tested Reactivity | Hu, Mk |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GSTA4 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human GSTA4. |
| Conjugation | Un-conjugated |
| Alternate Names | GSTA4; Glutathione S-Transferase Alpha 4; Glutathione S-Transferase A4; Glutathione S-Transferase A4-4; GST Class-Alpha Member 4; EC 2.5.1.18; S-(Hydroxyalkyl)Glutathione Lyase A4; Glutathione S-Aralkyltransferase A4; Glutathione S-Alkyltransferase A4; Glutathione S-Aryltransferase A4; Glutathione Transferase A4-4; GSTA4-4; GTA4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 26 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.005% Sodium azide and 4% Trehalose. |
| Preservative | 0.005% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | GSTA4 |
| Gene Full Name | Glutathione S-Transferase Alpha 4 |
| Background | Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis. [provided by RefSeq, Jul 2008] |
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. This isozyme has a high catalytic efficiency with 4-hydroxyalkenals such as 4-hydroxynonenal (4-HNE).. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 26 kDa |
| PTM | Acetylation. [UniProt] |
Images (4) Click the Picture to Zoom In
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ARG45199 anti-GSTA4 antibody IHC-P image
Immunohistochemistry: Human skeletal muscle stained with ARG45199 anti-GSTA4 antibody at 2 μg/ml dilution.
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ARG45199 anti-GSTA4 antibody WB image
Western blot: Human placenta, SH-SY5Y, HEPG2, and HEK293 stained with ARG45199 anti-GSTA4 antibody at 0.5 μg/ml dilution.
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ARG45199 anti-GSTA4 antibody FACS image
Flow Cytometry: U20S stained with ARG45199 anti-GSTA4 antibody at 1 µg/10^6 cells dilution.
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ARG45199 anti-GSTA4 antibody WB image
Western blot: Monkey skeletal muscle stained with ARG45199 anti-GSTA4 antibody at 0.5 μg/ml dilution.
