ARG64124

anti-GPSM2 antibody

anti-GPSM2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Cell Biology and Cellular Response antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes GPSM2
Tested Reactivity Hu
Predict Reactivity Dog
Tested Application IHC-P, WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name GPSM2
Antigen Species Human
Immunogen C-NRLKGKKYKTNSSTK
Conjugation Un-conjugated
Alternate Names LGN; Mosaic protein LGN; PINS; CMCS; G-protein-signaling modulator 2; DFNB82

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P5 µg/ml
WB0.01 - 0.03 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 29899 Human GPSM2

Swiss-port # P81274 Human G-protein-signaling modulator 2

Background The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82).[provided by RefSeq, Jan 2011]
Research Area Cell Biology and Cellular Response antibody; Signaling Transduction antibody
Calculated MW 77 kDa

Images (2) Click the Picture to Zoom In

  • ARG64124 anti-GPSM2 antibody WB image

    Western Blot: Human Brain (Cerebellum) lysate (35 µg protein in RIPA buffer) stained with ARG64124 anti-GPSM2 antibody at 0.01 µg/ml dilution.

  • ARG64124 anti-GPSM2 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human testis tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64124 anti-GPSM2 antibody at 5 µg/ml dilution followed by AP-staining.