ARG63319

anti-GPS1 / COPS1 antibody

anti-GPS1 / COPS1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Cell Biology and Cellular Response antibody; Neuroscience antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes GPS1 / COPS1
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Cow, Dog
Tested Application IHC-P, WB
Specificity This antibody is expected to recognise isoform 1 (NP_997657.1) and isoform 2 (NP_004118.3).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name GPS1 / COPS1
Antigen Species Human
Immunogen C-PANSQSRMSTNM
Conjugation Un-conjugated
Alternate Names COP9 signalosome complex subunit 1; SGN1; COPS1; G protein pathway suppressor 1; Signalosome subunit 1; CSN1; Protein MFH; JAB1-containing signalosome subunit 1; GPS-1

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P5 µg/ml
WB0.5 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 2873 Human GPS1

Swiss-port # Q13098 Human COP9 signalosome complex subunit 1

Background This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Research Area Cell Biology and Cellular Response antibody; Neuroscience antibody; Signaling Transduction antibody
Calculated MW 56 kDa

Images (4) Click the Picture to Zoom In

  • ARG63319 anti-GPS1 / COPS1 antibody WB image

    Western Blot: Human Testis lysate (RIPA buffer, 30µg total protein per lane) stained with ARG63319 anti-GPS1 / COPS1 antibody at 0.5 µg/ml dilution.

  • ARG63319 anti-GPS1 / COPS1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human prostate tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63319 anti-GPS1 / COPS1 antibody at 5 µg/ml dilution followed by AP-staining.

  • ARG63319 anti-GPS1 / COPS1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human testis tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63319 anti-GPS1 / COPS1 antibody at 5 µg/ml dilution followed by AP-staining.

  • ARG63319 anti-GPS1 / COPS1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human tonsil tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63319 anti-GPS1 / COPS1 antibody at 5 µg/ml dilution followed by AP-staining.