ARG10371
anti-GPBB + GPMM antibody [17B6]
anti-GPBB + GPMM antibody [17B6] for Purification,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [17B6] recognizes GPBB + GPMM |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | Puri, WB |
| Specificity | This antibody recognizes BB and MM isoenzymes. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 17B6 |
| Isotype | IgG1 |
| Target Name | GPBB + GPMM |
| Antigen Species | Human |
| Immunogen | Human GPBB. |
| Conjugation | Un-conjugated |
| Alternate Names | GPBB; EC 2.4.1.1; Glycogen phosphorylase, brain form |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.4) and 0.1% Sodium azide |
| Preservative | 0.1% Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P11216 Human Glycogen phosphorylase, brain form |
|---|---|
| Gene Symbol | PYGB |
| Gene Full Name | phosphorylase, glycogen; brain |
| Background | The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. [provided by RefSeq, Jul 2008] |
| Function | Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. [UniProt] |
| Calculated MW | 97 kDa |
| PTM | Phosphorylated (PubMed:27402852). Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A (By similarity). |
