ARG22879
anti-GLUT4 antibody [1F8]
anti-GLUT4 antibody [1F8] for ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat,Monkey,Pig,Rabbit
Cancer antibody; Cell Biology and Cellular Response antibody; Developmental Biology antibody; Metabolism antibody; Signaling Transduction antibody; Glucose uptake: Insulin Receptor Dependent Pathway Study antibody
Overview
| Product Description | Mouse Monoclonal antibody [1F8] recognizes GLUT4 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Mk, Pig, Rb |
| Species Does Not React With | Dog |
| Tested Application | ICC/IF, IHC-Fr, IHC-P, IP, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1F8 |
| Isotype | IgG1 |
| Target Name | GLUT4 |
| Antigen Species | Rat |
| Immunogen | Partially purified vesicles containing insulin-responsive glucose transporter 4. |
| Conjugation | Un-conjugated |
| Alternate Names | Glucose transporter type 4, insulin-responsive; GLUT4; GLUT-4; Solute carrier family 2, facilitated glucose transporter member 4 |
Application Instructions
| Application Suggestion |
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| Application Note | IHC-P: This product requires enzyme mediated antigen retrieval prior to staining of parrafin sections. Proteinase K is recomended for this purpose. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | PBS and 0.09% Sodium azide |
| Preservative | 0.09% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Slc2a4 |
| Gene Full Name | solute carrier family 2 (facilitated glucose transporter), member 4 |
| Background | This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008] |
| Function | Insulin-regulated facilitative glucose transporter. [UniProt] |
| Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Developmental Biology antibody; Metabolism antibody; Signaling Transduction antibody; Glucose uptake: Insulin Receptor Dependent Pathway Study antibody |
| Calculated MW | 55 kDa |
| PTM | Sumoylated. |
