ARG44338

anti-GATAD2B antibody

anti-GATAD2B antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes GATAD2B
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name GATAD2B
Antigen Species Human
Immunogen Human GATAD2B recombinant fusion protein (a.a. sequence: 1-120).
Conjugation Un-conjugated
Alternate Names GATAD2B; GATA Zinc Finger Domain Containing 2B; P66beta; Transcription Repressor P66 Beta Component Of The MeCP1 Complex; GATA Zinc Finger Domain-Containing Protein 2B; Transcriptional Repressor P66-Beta; KIAA1150; P66/P68; GANDS; MRD18; P68

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:200
IPAssay-dependent
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS, 0.02% sodium azide and 50% Glycerol.
Preservative 0.02% sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 229542 Mouse GATAD2B

GeneID: 57459 Human GATAD2B

Swiss-port # Q8VHR5 Mouse Transcriptional repressor p66-beta

Swiss-port # Q8WXI9 Human Transcriptional repressor p66-beta

Gene Symbol GATAD2B
Gene Full Name GATA Zinc Finger Domain Containing 2B
Background This gene encodes a zinc finger protein transcriptional repressor. The encoded protein is part of the methyl-CpG-binding protein-1 complex, which represses gene expression by deacetylating methylated nucleosomes. Mutations in this gene are linked to intellectual disability and dysmorphic features associated with cognitive disability.
Function Transcriptional repressor.
Cellular Localization Chromosome, Nucleus
Calculated MW 65 kDa
PTM Isopeptide bond, Phosphoprotein, Ubl conjugation

Images (3) Click the Picture to Zoom In

  • ARG44338 anti-GATAD2B antibody WB image

    Western blot: HeLa and Jurkat stained with ARG44338 anti-GATAD2B antibody at 1:1000 dilution.

  • ARG44338 anti-GATAD2B antibody WB image

    Western blot: Mouse Kidney stained with ARG44338 anti-GATAD2B antibody at 1:1000 dilution.

  • ARG44338 anti-GATAD2B antibody IHC-P image

    Immunohistochemistry: Mouse pancreas stained with ARG44338 anti-GATAD2B antibody at 1:100 dilution.