ARG57697
anti-GARS antibody
anti-GARS antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GARS |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GARS |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human GARS. |
| Conjugation | Un-conjugated |
| Alternate Names | DSMAV; HMN5; Glycine--tRNA ligase; Glycyl-tRNA synthetase; SMAD1; CMT2D; EC 6.1.1.14; Diadenosine tetraphosphate synthetase; GlyRS; AP-4-A synthetase |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | U87 | ||||||||
| Observed Size | ~ 83 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | GARS |
| Gene Full Name | glycyl-tRNA synthetase |
| Background | This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. [provided by RefSeq, Jul 2008] |
| Function | Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. [UniProt] |
| Cellular Localization | Cell projection, Cytoplasm, Mitochondrion, axon. [UniProt] |
| Calculated MW | 83 kDa |
Images (2) Click the Picture to Zoom In
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ARG57697 anti-GARS antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse brain stained with ARG57697 anti-GARS antibody at 1:100 dilution.
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ARG57697 anti-GARS antibody WB image
Western blot: 25 µg of U87 cell lysate stained with ARG57697 anti-GARS antibody at 1:5000 dilution.
