ARG58724
anti-GAMT antibody
anti-GAMT antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GAMT |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GAMT |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-236 of Human GAMT (NP_000147.1). |
| Conjugation | Un-conjugated |
| Alternate Names | CCDS2; EC 2.1.1.2; TP53I2; PIG2; HEL-S-20; Guanidinoacetate N-methyltransferase |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | HeLa | ||||||||
| Observed Size | 29 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O35969 Mouse Guanidinoacetate N-methyltransferase Swiss-port # Q14353 Human Guanidinoacetate N-methyltransferase |
|---|---|
| Gene Symbol | GAMT |
| Gene Full Name | guanidinoacetate N-methyltransferase |
| Background | The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13. [provided by RefSeq, Feb 2012] |
| Calculated MW | 26 kDa |
Images (2) Click the Picture to Zoom In
-
ARG58724 anti-GAMT antibody ICC/IF image
Immunofluorescence: U2OS cells stained with ARG58724 anti-GAMT antibody.
-
ARG58724 anti-GAMT antibody WB image
Western blot: 25 µg of HeLa cell lysate stained with ARG58724 anti-GAMT antibody at 1:1000 dilution.
