ARG45399
anti-GALNS antibody
anti-GALNS antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GALNS |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GALNS |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human GALNS. |
| Conjugation | Un-conjugated |
| Alternate Names | MPS4A; EC 3.1.6.4; Chondroitinsulfatase; GAS; N-acetylgalactosamine-6-sulfatase; GalNAc6S sulfatase; GalN6S; Chondroitinase; GALNAC6S; N-acetylgalactosamine-6-sulfate sulfatase; Galactose-6-sulfate sulfatase |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 58 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | GALNS |
| Gene Full Name | Galactosamine (N-Acetyl)-6-Sulfatase |
| Background | This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq, Jul 2008] |
| Function | Hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate. [UniProt] |
| Cellular Localization | Lysosome. [UniProt] |
| Calculated MW | 58 kDa |
| PTM | Disulfide bond; Glycoprotein. [UniProt] |
Images (5) Click the Picture to Zoom In
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ARG45399 anti-GALNS antibody IHC-P image
Immunohistochemistry: Human lung cancer stained with ARG45399 anti-GALNS antibody at 1 μg/ml dilution.
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ARG45399 anti-GALNS antibody WB image
Western blot: MCF-7 stained with ARG45399 anti-GALNS antibody at 0.5 μg/ml dilution.
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ARG45399 anti-GALNS antibody IHC-P image
Immunohistochemistry: Rat liver stained with ARG45399 anti-GALNS antibody at 1 μg/ml dilution.
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ARG45399 anti-GALNS antibody WB image
Western blot: Rat kidney stained with ARG45399 anti-GALNS antibody at 0.5 μg/ml dilution.
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ARG45399 anti-GALNS antibody IHC-P image
Immunohistochemistry: Mouse liver stained with ARG45399 anti-GALNS antibody at 1 μg/ml dilution.
