ARG65227
anti-GABAA Receptor gamma 2 antibody
anti-GABAA Receptor gamma 2 antibody for Western blot and Mouse,Rat
Neuroscience antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes GABAA Receptor gamma 2 |
|---|---|
| Tested Reactivity | Ms, Rat |
| Predict Reactivity | Hu, Cow |
| Tested Application | WB |
| Specificity | This antibody is expected to recognize all reported isoforms: NP_944494.1; NP_000807.2; NP_944493.2. Note the aa numbers used in the name are from NP_944494.1. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GABAA Receptor gamma 2 |
| Antigen Species | Human |
| Immunogen | C-NNATHLQERDE |
| Conjugation | Un-conjugated |
| Alternate Names | A; CAE2; ECA2; GEFSP3; Gamma-aminobutyric acid receptor subunit gamma-2; GABA |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P18508 Rat Gamma-aminobutyric acid receptor subunit gamma-2 Swiss-port # P22723 Mouse Gamma-aminobutyric acid receptor subunit gamma-2 |
|---|---|
| Background | This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| Research Area | Neuroscience antibody |
| Calculated MW | 54 kDa |
| PTM | Palmitoylated by ZDHHC3/GODZ; which may affect presynaptic clustering and/or cell surface stability. |
Images (1) Click the Picture to Zoom In
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ARG65227 anti-GABAA Receptor gamma 2 antibody WB image
Western blot: Mouse Brain lysate (35 µg protein in RIPA buffer) stained with ARG65227 anti-GABAA Receptor gamma 2 antibody at 2 µg/ml dilution.
