ARG22235
anti-GABAA Receptor delta antibody [S151-3]
anti-GABAA Receptor delta antibody [S151-3] for ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Mouse Monoclonal antibody [S151-3] recognizes GABAA Receptor delta |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, WB |
| Specificity | Detects ~55kDa. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | S151-3 |
| Isotype | IgG2a |
| Target Name | GABAA Receptor delta |
| Antigen Species | Rat |
| Immunogen | Synthetic peptide around aa. 15-34 of Rat GABAA Receptor delta |
| Conjugation | Un-conjugated |
| Alternate Names | A; EJM7; GEFSP5; Gamma-aminobutyric acid receptor subunit delta; EIG10; GABA |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | PBS (pH 7.4), 0.09% Sodium azide and 50% Glycerol |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Gabrd |
| Gene Full Name | gamma-aminobutyric acid (GABA) A receptor, delta |
| Background | Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
| Function | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. [UniProt] |
| Cellular Localization | Cell Junction, Cell membrane, postsynaptic cell membrane, Synapse |
| Calculated MW | 51 kDa |
Images (1) Click the Picture to Zoom In
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ARG22235 anti-GABAA Receptor delta antibody [S151-3] WB image
Western blot: Rat cell line lysates stained with ARG22235 anti-GABAA Receptor delta antibody [S151-3] at 1:1000 dilution.
