ARG64794
anti-GABAA Receptor beta 3 antibody
anti-GABAA Receptor beta 3 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Neuroscience antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes GABAA Receptor beta 3 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Cow, Dog |
| Tested Application | IHC-P |
| Specificity | This antibody is expected to recognize both reported isoforms (NP_000805.1, NP_068712.1). |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GABAA Receptor beta 3 |
| Antigen Species | Human |
| Immunogen | C-EKTAKAKNDRSK |
| Conjugation | Un-conjugated |
| Alternate Names | Gamma-aminobutyric acid receptor subunit beta-3; A; ECA5; GABA |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P28472 Human Gamma-aminobutyric acid receptor subunit beta-3 |
|---|---|
| Background | This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two genes encoding related subunits of the family. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2010] |
| Research Area | Neuroscience antibody |
| Calculated MW | 54 kDa |
Images (1) Click the Picture to Zoom In
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ARG64794 anti-GABAA Receptor beta 3 antibody IHC-P image
Immunohistochemistry: Paraffin embedded Human Cortex. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG64794 anti-GABAA Receptor beta 3 antibody at 2.5 µg/ml dilution followed by AP-staining.
