ARG67232
anti-Fibronectin antibody
anti-Fibronectin antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Drosophila,Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Fibronectin |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Drosophila |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Fibronectin |
| Conjugation | Un-conjugated |
| Alternate Names | FN1; Fibronectin 1; CIG; Cold-Insoluble Globulin; Lnc-ABCA12-8; GFND2; LETS; FINC; MSF; Migration-Stimulating Factor; Fibronectin; FN; Epididymis Secretory Sperm Binding Protein; SMDCF; ED-B; GFND; FNZ |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 100 mM Tris Glycine (pH 7.0), 0.025% ProClin 300 and 20% Glycerol. |
| Preservative | 0.025% ProClin 300 |
| Stabilizer | 20% Glycerol |
| Concentration | 1.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | FN1 |
| Gene Full Name | Fibronectin 1 |
| Background | This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined. [provided by RefSeq, Jan 2016] |
| Function | Acts as a ligand for the LILRB4 receptor, inhibiting FCGR1A/CD64-mediated monocyte activation. [Uniprot] |
| Cellular Localization | Extracellular matrix, Secreted. [Uniprot] |
| Calculated MW | 272 kDa |
| PTM | Disulfide bond; Glycoprotein; Isopeptide bond; Oxidation; Phosphoprotein; Pyrrolidone carboxylic acid; Sulfation. [Uniprot] |
Images (3) Click the Picture to Zoom In
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ARG67232 anti-Fibronectin antibody IHC-P image
Immunohistochemistry: Breast Carcinoma stained with ARG67232 anti-Fibronectin antibody at 1:100 dilution.
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ARG67232 anti-Fibronectin antibody ICC/IF image
Immunofluorescence: PANC-1 stained with ARG67232 anti-Fibronectin antibody at 1:200 dilution.
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ARG67232 anti-Fibronectin antibody IHC-P image
Immunohistochemistry: Breast Carcinoma stained with ARG67232 anti-Fibronectin antibody at 1:100 dilution.
