ARG45354
anti-Fetuin B antibody [6N19]
anti-Fetuin B antibody [6N19] for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody [6N19] recognizes Fetuin B |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 6N19 |
| Isotype | IgG1 |
| Target Name | Fetuin B |
| Antigen Species | Human |
| Immunogen | Recombinant Human Fetuin B. |
| Conjugation | Un-conjugated |
| Alternate Names | FETUB; Fetuin B; Fetuin-Like Protein IRL685; Fetuin-B; 16G2; Gugu; IRL685 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein G chromatography |
| Buffer | PBS |
| Concentration | 0.2 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | FETUB |
| Gene Full Name | Fetuin B |
| Background | The protein encoded by this gene is a member of the fetuin family, part of the cystatin superfamily of cysteine protease inhibitors. Fetuins have been implicated in several diverse functions, including osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors, and response to systemic inflammation. This protein may be secreted by cells. [provided by RefSeq, Jul 2008] |
| Function | Protease inhibitor required for egg fertilization. Required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 42 kDa |
| PTM | Disulfide bond; Glycoprotein; Phosphoprotein. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG45354 anti-Fetuin B antibody [6N19] IHC-P image
Immunohistochemistry: Human placental stained with ARG45354 anti-Fetuin B antibody [6N19].
