ARG45476
anti-FYCO1 antibody
anti-FYCO1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes FYCO1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FYCO1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human FYCO1. |
| Conjugation | Un-conjugated |
| Alternate Names | FYCO1; FYVE And Coiled-Coil Domain Autophagy Adaptor 1; ZFYVE7; FYVE And Coiled-Coil Domain-Containing Protein 1; Zinc Finger FYVE Domain-Containing Protein 7; FYVE And Coiled-Coil Domain Containing 1; FLJ13335; RUN And FYVE Domain Containing 3; CTRCT18; CATC2; RUFY3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 167 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8VDC1 Mouse FYVE and coiled-coil domain-containing protein 1 Swiss-port # Q9BQS8 Human FYVE and coiled-coil domain-containing protein 1 |
|---|---|
| Gene Symbol | FYCO1 |
| Gene Full Name | FYVE And Coiled-Coil Domain Autophagy Adaptor 1 |
| Background | The gene encodes a Rab7 adapter protein that is implicated in the microtubule transport of autophagosomes. The encoded protein contains a RUN domain, a FYVE-type zinc finger domain, and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P), the autophagosome marker LC3, and the kinesin KIF5. Mutations in this gene are associated with inclusion body myositis (IBM) and autosomal recessive congenital cataracts (CATC2). [provided by RefSeq, Aug 2020] |
| Function | May mediate microtubule plus end-directed vesicle transport. [UniProt] |
| Cellular Localization | Cytoplasmic vesicle; Endosome; Lysosome. [UniProt] |
| Calculated MW | 162 kDa |
| PTM | Acetylation; Phosphoprotein. [UniProt] |
Images (5) Click the Picture to Zoom In
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ARG45476 anti-FYCO1 antibody IHC-P image
Immunohistochemistry: Human thyroid cancer stained with ARG45476 anti-FYCO1 antibody at 2 μg/ml dilution.
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ARG45476 anti-FYCO1 antibody WB image
Western blot: HUVEC stained with ARG45476 anti-FYCO1 antibody at 0.5 μg/ml dilution.
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ARG45476 anti-FYCO1 antibody FACS image
Flow Cytometry: Jurkat stained with ARG45476 anti-FYCO1 antibody at 1 µg/10^6 cells dilution.
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ARG45476 anti-FYCO1 antibody WB image
Western blot: Rat testis stained with ARG45476 anti-FYCO1 antibody at 0.5 μg/ml dilution.
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ARG45476 anti-FYCO1 antibody WB image
Western blot: Mouse heart stained with ARG45476 anti-FYCO1 antibody at 0.5 μg/ml dilution.
