ARG44045

anti-FIP200 antibody

anti-FIP200 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes FIP200
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name FIP200
Antigen Species Human
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1280-1400 of Human FIP200 (NP_055596.3).
Conjugation Un-conjugated
Alternate Names RB1CC1; RB1 Inducible Coiled-Coil 1; FIP200; KIAA0203; PPP1R131; ATG17; FAK Family Kinase-Interacting Protein Of 200 KDa; 200 KDa FAK Family Kinase-Interacting Protein; Phosphatase 1, Regulatory Subunit 131; RB1-Inducible Coiled-Coil Protein 1; DRAGOU14; Cc1; RBICC; CC1

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:500 - 1:2000
WB1:50 - 1:200
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.01% Thimerosal and 50% Glycerol.
Preservative 0.01% Thimerosal
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 12421 Mouse RB1CC1

GeneID: 9821 Human RB1CC1

Swiss-port # Q8TDY2 Human RB1-inducible coiled-coil protein 1

Swiss-port # Q9ESK9 Mouse RB1-inducible coiled-coil protein 1

Gene Symbol RB1CC1
Gene Full Name RB1 Inducible Coiled-Coil 1
Background The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Function Plays an indispensable role in fetal hematopoiesis and in the regulation of neuronal homeostasis.
Cellular Localization Cytoplasm, Lysosome, Nucleus
Calculated MW 183 kDa
PTM Phosphoprotein

Images (4) Click the Picture to Zoom In

  • ARG44045 anti-FIP200 antibody IHC-P image

    Immunohistochemistry: Human lung cancer stained with ARG44045 anti-FIP200 antibody at 1:100 dilution.

  • ARG44045 anti-FIP200 antibody WB image

    Western blot: Mouse Testis and Rat Testis stained with ARG44045 anti-FIP200 antibody at 1:1000 dilution.

  • ARG44045 anti-FIP200 antibody IHC-P image

    Immunohistochemistry: Mouse spleen stained with ARG44045 anti-FIP200 antibody at 1:100 dilution.

  • ARG44045 anti-FIP200 antibody WB image

    Western blot: U2OS and HeLa stained with ARG44045 anti-FIP200 antibody at 1:1000 dilution.