ARG58627
anti-FGF4 antibody
anti-FGF4 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes FGF4 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FGF4 |
| Antigen Species | Human |
| Immunogen | Highly pure (> 98%) recombinant Human FGF4. |
| Conjugation | Un-conjugated |
| Alternate Names | K-FGF; HST-1; FGF-4; Transforming protein KS3; HSTF-1; Heparin secretory-transforming protein 1; Fibroblast growth factor 4; KFGF; HST; Heparin-binding growth factor 4; HBGF-4; HSTF1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Heat mediated was performed in Sodium citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS and 0.02% Sodium azide |
| Preservative | 0.02% Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | FGF4 |
| Gene Full Name | fibroblast growth factor 4 |
| Background | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq, Jul 2008] |
| Function | Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal limb and cardiac valve development during embryogenesis. [UniProt] |
| Calculated MW | 22 kDa |
Images (1) Click the Picture to Zoom In
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ARG58627 anti-FGF4 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded breast tissue from a breast carcinoma stained with ARG58627 anti-FGF4 antibody at 0.25 µg/ml, overnight at 4˚C. Antigen Retrieval: Heat mediated was performed in Sodium citrate buffer (pH 6.0).
