ARG67149
anti-FDX1 / Ferredoxin 1 antibody
anti-FDX1 / Ferredoxin 1 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Polyclonal antibody recognizes FDX1 / Ferredoxin 1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FDX1 / Ferredoxin 1 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within human FDX1 / Ferredoxin 1. |
| Conjugation | Un-conjugated |
| Alternate Names | LOH11CR1D; Hepatoredoxin; ADX; Adrenal ferredoxin; FDX; Ferredoxin-1; Adrenodoxin, mitochondrial |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Observed Size | 13 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.3) with 0.01% Sodium azide, 50% Glycerol and 0.2% BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 50% Glycerol and 0.2% BSA. |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | FDX1 |
| Gene Full Name | ferredoxin 1 |
| Background | This gene encodes a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to mitochondrial cytochrome P450, involved in steroid, vitamin D, and bile acid metabolism. Pseudogenes of this functional gene are found on chromosomes 20 and 21. [provided by RefSeq, Aug 2011] |
| Function | Participates in the synthesis of thyroid hormones. Essential for the synthesis of various steroid hormones, participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. [UniProt] |
| Cellular Localization | Mitochondrion matrix. [UniProt] |
| Calculated MW | 19 kDa |
Images (3) Click the Picture to Zoom In
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ARG67149 anti-FDX1 / Ferredoxin 1 antibody WB image
Western blot: Jurkat, THP1 and A549 stained with ARG67149 anti-FDX1 / Ferredoxin 1 antibody.
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ARG67149 anti-FDX1 / Ferredoxin 1 antibody WB image
Western blot: Rat kidney stained with ARG67149 anti-FDX1 / Ferredoxin 1 antibody.
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ARG67149 anti-FDX1 / Ferredoxin 1 antibody WB image
Western blot: Mouse kidney and Mouse muscle stained with ARG67149 anti-FDX1 / Ferredoxin 1 antibody.
