ARG58670
anti-FDX1 / Ferredoxin 1 antibody
anti-FDX1 / Ferredoxin 1 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes FDX1 / Ferredoxin 1. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FDX1 / Ferredoxin 1 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-184 of Human FDX1 / Ferredoxin 1. |
| Conjugation | Un-conjugated |
| Alternate Names | LOH11CR1D; Hepatoredoxin; ADX; Adrenal ferredoxin; FDX; Ferredoxin-1; Adrenodoxin, mitochondrial |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | K562 | ||||
| Observed Size | 14 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | FDX1 |
| Gene Full Name | ferredoxin 1 |
| Background | This gene encodes a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to mitochondrial cytochrome P450, involved in steroid, vitamin D, and bile acid metabolism. Pseudogenes of this functional gene are found on chromosomes 20 and 21. [provided by RefSeq, Aug 2011] |
| Function | Participates in the synthesis of thyroid hormones. Essential for the synthesis of various steroid hormones, participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. [UniProt] |
| Cellular Localization | Mitochondrion matrix. [UniProt] |
| Calculated MW | 19 kDa |
Images (1) Click the Picture to Zoom In
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ARG58670 anti-FDX1 / Ferredoxin 1 antibody WB image
Western blot: 25 µg of K562 cell lysate stained with ARG58670 anti-FDX1 / Ferredoxin 1 antibody at 1:1000 dilution.
