ARG43831

anti-FDX1 / Ferredoxin 1 antibody

anti-FDX1 / Ferredoxin 1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes FDX1 / Ferredoxin 1.
Tested Reactivity Hu, Ms
Tested Application IHC-P, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name FDX1 / Ferredoxin 1
Immunogen Synthetic peptide from human FDX1 / Ferredoxin 1.
Conjugation Un-conjugated
Alternate Names LOH11CR1D; Hepatoredoxin; ADX; Adrenal ferredoxin; FDX; Ferredoxin-1; Adrenodoxin, mitochondrial

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50-1:100
IP1:20
WB1:500-1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity Purified
Buffer Tris-Glycine (pH 7.4) with 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Preservative 0.01% Sodium azide
Stabilizer 40% Glycerol and 0.05% BSA
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 14148 Mouse FDX1

GeneID: 2230 Human FDX1

Swiss-port # P10109 Human Adrenodoxin, mitochondrial

Swiss-port # P46656 Mouse Adrenodoxin, mitochondrial

Gene Symbol FDX1
Gene Full Name ferredoxin 1
Background This gene encodes a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to mitochondrial cytochrome P450, involved in steroid, vitamin D, and bile acid metabolism. Pseudogenes of this functional gene are found on chromosomes 20 and 21. [provided by RefSeq, Aug 2011]
Function Participates in the synthesis of thyroid hormones. Essential for the synthesis of various steroid hormones, participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. [UniProt]
Cellular Localization Mitochondrion matrix. [UniProt]
Calculated MW 19 kDa

Images (2) Click the Picture to Zoom In

  • ARG43831 anti-FDX1 / Ferredoxin 1 antibody IHC-P image

    Immunohistochemistry: Human colon cancer stained with ARG43831 anti-FDX1 / Ferredoxin 1 antibody.

  • ARG43831 anti-FDX1 / Ferredoxin 1 antibody WB image

    Western blot: 3T3 cell stained with ARG43831 anti-FDX1 / Ferredoxin 1 antibody.