ARG44831
anti-FCAMR antibody
anti-FCAMR antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
Product Description | Mouse Monoclonal antibody recognizes FCAMR |
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Tested Reactivity | Hu |
Tested Application | IHC-P |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG2a |
Target Name | FCAMR |
Antigen Species | Human |
Conjugation | Un-conjugated |
Alternate Names | FCAMR; Fc Alpha And Mu Receptor; Fc Alpha/Mu Receptor; Fcalpha/MuR; FKSG87; FCA/MR; CD351; High Affinity Immunoglobulin Alpha And Immunoglobulin Mu Fc Receptor; Fc Receptor, IgA, IgM, High Affinity; Fc Fragment Of IgA And IgM Receptor; Receptor For Fc Fragment Of IgA And IgM; Immunity Related Factor; CD351 Antigen |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Protein A purification |
Buffer | PBS with 0.09% sodium azide |
Preservative | 0.09% sodium azide |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
Database Links |
Swiss-port # Q8WWV6 Human High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor |
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Gene Symbol | FCAMR |
Gene Full Name | Fc Alpha And Mu Receptor |
Background | Predicted to enable IgA binding activity; IgM binding activity; and transmembrane signaling receptor activity. Predicted to be involved in adaptive immune response. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] |
Function | Functions as a receptor for the Fc fragment of IgA and IgM. Binds IgA and IgM with high affinity and mediates their endocytosis. May function in the immune response to microbes mediated by IgA and IgM. [UniProt] |
Cellular Localization | Cell membrane, Membrane. [UniProt] |
PTM | Disulfide bond, Glycoprotein. [UniProt] |
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