ARG63352

anti-FBXL12 antibody

anti-FBXL12 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human

Cell Biology and Cellular Response antibody

Overview

Product Description Goat Polyclonal antibody recognizes FBXL12
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Dog
Tested Application IHC-P
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name FBXL12
Antigen Species Human
Immunogen RACPKESMDWWM
Conjugation Un-conjugated
Alternate Names Fbl12; F-box and leucine-rich repeat protein 12; F-box protein FBL12; F-box/LRR-repeat protein 12

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P4 - 6 µg/ml
Application Note IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 54850 Human FBXL12

Swiss-port # Q9NXK8 Human F-box/LRR-repeat protein 12

Background Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Research Area Cell Biology and Cellular Response antibody
Calculated MW 37 kDa

Images (1) Click the Picture to Zoom In

  • ARG63352 anti-FBXL12 antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Lung. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63352 anti-FBXL12 antibody at 4 µg/ml dilution followed by HRP-staining.