ARG45293

anti-FAM134B antibody

anti-FAM134B antibody for Flow cytometry,ICC/IF,Western blot and Human

Overview

Product Description Polyclonal antibody recognizes FAM134B
Tested Reactivity Hu
Tested Application FACS, ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name FAM134B
Antigen Species Human
Immunogen Recombinant protein containing to human FAM134B.
Conjugation Un-conjugated
Alternate Names RETREG1; Reticulophagy Regulator 1; JK1; FAM134B; Family With Sequence Similarity 134 Member B; Reticulophagy Receptor 1; FLJ20152; Family With Sequence Similarity 134, Member B; Reticulophagy Receptor FAM134B; Protein FAM134B; JK-1

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1 - 3 µg/10^6 cells
ICC/IF5 μg/ml
WB0.25-0.5 μg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size 55 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
Stabilizer 4% Trehalose
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 54463 Human FAM134B

Swiss-port # Q9H6L5 Human Reticulophagy receptor FAM134B

Gene Symbol RETREG1 
Gene Full Name Reticulophagy Regulator 1
Background he protein encoded by this gene is a cis-Golgi transmembrane protein that may be necessary for the long-term survival of nociceptive and autonomic ganglion neurons. Mutations in this gene are a cause of hereditary sensory and autonomic neuropathy type IIB (HSAN IIB), and this gene may also play a role in susceptibility to vascular dementia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Function Endoplasmic reticulum (ER)-anchored autophagy regulator which mediates ER delivery into lysosomes through sequestration into autophagosomes. [UniProt]
Cellular Localization Endoplasmic reticulum; Golgi apparatus; Membrane. [UniProt]
Calculated MW 55 kDa
PTM Phosphoprotein. [UniProt]

Images (3) Click the Picture to Zoom In

  • ARG45293 anti-FAM134B antibody ICC/IF image

    Immunofluorescence: U87 stained with ARG45293 anti-FAM134B antibody at 5 ug/ml dilution.

  • ARG45293 anti-FAM134B antibody WB image

    Western blot: U-87MG and Hela stained with ARG45293 anti-FAM134B antibody at 0.5 μg/ml dilution.

  • ARG45293 anti-FAM134B antibody FACS image

    Flow Cytometry: HL-60 stained with ARG45293 anti-FAM134B antibody at 1 µg/10^6 cells dilution.