ARG56532
anti-FABP2 / Intestinal FABP antibody
anti-FABP2 / Intestinal FABP antibody for Western blot and Human,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes FABP2 / Intestinal FABP |
|---|---|
| Tested Reactivity | Hu, Rat |
| Tested Application | WB |
| Specificity | This antibody does not react to FABP1, FABP3 and FABP4. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FABP2 / Intestinal FABP |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around aa. 33-40 of Human Intestinal FABP. |
| Conjugation | Un-conjugated |
| Alternate Names | Intestinal-type fatty acid-binding protein; I-FABP; Fatty acid-binding protein, intestinal; Fatty acid-binding protein 2; FABPI |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P02693 Rat Fatty acid-binding protein, intestinal Swiss-port # P12104 Human Fatty acid-binding protein, intestinal |
|---|---|
| Gene Symbol | FABP2 |
| Gene Full Name | fatty acid binding protein 2, intestinal |
| Background | The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. [provided by RefSeq, Jul 2008] |
| Function | FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. [UniProt] |
| Calculated MW | 15 kDa |
Images (1) Click the Picture to Zoom In
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ARG56532 anti-FABP2 / Intestinal FABP antibody WB image
Western blot: 1) 0.4 µg of Rat Recombinant FABP1, 2) 0.025 µg of Rat Recombinant FABP2, 3) 0.050 µg of Rat Recombinant FABP2, 4) 0.4 µg of Human Recombinant FABP3, 5) 0.4 µg of Mouse Recombinant FABP4, 6) 0.4 µg of Mouse Recombinant FABP5, and 7) 30 µg of Human Duodenum Homogenate stained with ARG56532 anti-FABP2 / Intestinal FABP antibody.
