ARG45352
anti-Eph receptor B6 antibody [9B17]
anti-Eph receptor B6 antibody [9B17] for IHC-Formalin-fixed paraffin-embedded sections and Mouse
Overview
| Product Description | Rat Monoclonal antibody [9B17] recognizes Eph receptor B6 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | IHC-P |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | 9B17 |
| Isotype | IgG2 |
| Target Name | Eph receptor B6 |
| Antigen Species | Mouse |
| Immunogen | Recombinant Mouse Eph receptor B6. |
| Conjugation | Un-conjugated |
| Alternate Names | EPHB6; EPH Receptor B6; HEP; Tyrosine-Protein Kinase-Defective Receptor EPH-6; Ephrin Type-B Receptor 6; Human Kinase-Defective Eph-Family Receptor Protein; EC 2.7.10.1; EphB6 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein G/A chromatography |
| Buffer | PBS |
| Concentration | 0.2 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | EphB6 |
| Gene Full Name | EPH Receptor B6 |
| Background | This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| Function | Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2 . [UniProt] |
| Cellular Localization | Cell membrane; Membrane; Secreted. [UniProt] |
| Calculated MW | 110 kDa |
| PTM | Glycoprotein. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG45352 anti-Eph receptor B6 antibody [9B17] IHC-P image
Immunohistochemistry: Mouse kidney stained with ARG45352 anti-Eph receptor B6 antibody [9B17].
