ARG44148
anti-EMR1 F4/80 antibody
anti-EMR1 F4/80 antibody for IHC-Formalin-fixed paraffin-embedded sections and Mouse,Rat
Mouse Inflammatory Cell Marker antibody; Macrophage Marker antibody
Overview
| Product Description | Rabbit Polyclonal recognizes EMR1 F4/80 |
|---|---|
| Tested Reactivity | Ms, Rat |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | EMR1 F4/80 |
| Antigen Species | Mouse |
| Immunogen | Mouse EMR1 F4/80 recombinant protein (Position: G27-S230). |
| Conjugation | Un-conjugated |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q5Y4N8 Rat Adhesion G protein-coupled receptor E2 Swiss-port # Q61549 Mouse Adhesion G protein-coupled receptor E1 |
|---|---|
| Gene Symbol | Adgre1 |
| Gene Full Name | adhesion G protein-coupled receptor E1 |
| Background | EMR1 F4/80 has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
| Function | EMR1 F4/80: Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development. [UniProt] |
| Highlight | Related Antibody Duos and Panels: ARG30326 Inflammatory Cell Antibody Panel (for mouse) Related products: EMR1 F4/80 antibodies; EMR1 F4/80 Duos / Panels; Anti-Rat IgG secondary antibodies; Related news: Exploring Antiviral Immune Response |
| Research Area | Mouse Inflammatory Cell Marker antibody; Macrophage Marker antibody |
| Calculated MW | 98 kDa |
Images (4) Click the Picture to Zoom In
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ARG44148 anti-EMR1 F4/80 antibody IHC-P image
Immunohistochemistry: Rat liver stained with ARG44148 anti-EMR1 F4/80 antibody at 2 μg/ml dilution.
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ARG44148 anti-EMR1 F4/80 antibody IHC-P image
Immunohistochemistry: Mouse spleen stained with ARG44148 anti-EMR1 F4/80 antibody at 2 μg/ml dilution.
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ARG44148 anti-EMR1 F4/80 antibody IHC-P image
Immunohistochemistry: Rat liver stained with ARG44148 anti-EMR1 F4/80 antibody at 5 μg/ml dilution.
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ARG44148 anti-EMR1 F4/80 antibody IHC-P image
Immunohistochemistry: Mouse liver stained with ARG44148 anti-EMR1 F4/80 antibody at 5 μg/ml dilution.
