ARG45785
anti-EAAT2 antibody
anti-EAAT2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes EAAT2 |
|---|---|
| Tested Reactivity | Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | EAAT2 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human EAAT2. |
| Conjugation | Un-conjugated |
| Alternate Names | SLC1A2; Solute Carrier Family 1 Member 2; EAAT2; GLT1; Excitatory Amino Acid Transporter 2; GLT-1; HBGT; Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2; Sodium-Dependent Glutamate/Aspartate Transporter 2; Glutamate/Aspartate Transporter II; Human Brain Glutamate Transporter; Glutamate Transporter-1; Excitotoxic Amino Acid Transporter 2; EIEE41; DEE41 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 65 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P31596 Rat Excitatory amino acid transporter 2 Swiss-port # P43006 Mouse Excitatory amino acid transporter 2 |
|---|---|
| Gene Symbol | SLC1A2 |
| Gene Full Name | Solute Carrier Family 1 Member 2 |
| Background | This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2017] |
| Function | Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. [UniProt] |
| Cellular Localization | Cell membrane; Membrane. [UniProt] |
| Calculated MW | 62 kDa |
| PTM | Glycoprotein; Lipoprotein; Palmitate; Phosphoprotein. [UniProt] |
