ARG52264
anti-Dopamine Transporter antibody, Extracellular Loop 2
anti-Dopamine Transporter antibody, Extracellular Loop 2 for IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Primates
Neuroscience antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Dopamine Transporter |
|---|---|
| Tested Reactivity | Hu, NHuPrm |
| Tested Application | IHC-Fr, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Dopamine Transporter |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to amino acid residues from the extracellular loop 2 region conjugated to KLH |
| Conjugation | Un-conjugated |
| Alternate Names | PKDYS; Sodium-dependent dopamine transporter; Solute carrier family 6 member 3; DAT1; DAT; DA transporter |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|---|---|
| Application Note | Specific for the ~88k DAT protein in Western blots. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity Purified |
| Buffer | 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol |
| Stabilizer | 0.1 mg/ml BSA, 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q01959 Human Sodium-dependent dopamine transporter |
|---|---|
| Gene Symbol | SLC6A3 |
| Gene Full Name | solute carrier family 6 (neurotransmitter transporter), member 3 |
| Background | The dopamine transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). Levels of DAT protein expression are altered by chronic drug administration (Wilson et al., 1996). |
| Research Area | Neuroscience antibody |
| Calculated MW | 68 kDa |
Images (1) Click the Picture to Zoom In
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ARG52264 anti-Dopamine Transporter antibody, Extracellular Loop 2 WB image
Western blot: human caudate lysate stained with ARG52264 anti-Dopamine Transporter antibody, Extracellular Loop 2 showing specific immunolabeling of the ~88k DAT protein.
