ARG58545
anti-Deoxyguanosine kinase antibody
anti-Deoxyguanosine kinase antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Deoxyguanosine kinase |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Deoxyguanosine kinase |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 241-271 of Human Deoxyguanosine kinase. |
| Conjugation | Un-conjugated |
| Alternate Names | dGK; EC 2.7.1.113; Deoxyguanosine kinase, mitochondrial; MTDPS3 |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | HeLa |
Properties
| Form | Liquid |
|---|---|
| Purification | Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Buffer | PBS and 0.09% (W/V) Sodium azide. |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q16854 Human Deoxyguanosine kinase, mitochondrial |
|---|---|
| Gene Symbol | DGUOK |
| Gene Full Name | deoxyguanosine kinase |
| Background | In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
| Function | Required for the phosphorylation of several deoxyribonucleosides and certain nucleoside analogs widely employed as antiviral and chemotherapeutic agents. [UniProt] |
| Calculated MW | 32 kDa |
Images (1) Click the Picture to Zoom In
-
ARG58545 anti-Deoxyguanosine kinase antibody WB image
Western blot: 20 µg of HeLa cell lysate stained with ARG58545 anti-Deoxyguanosine kinase antibody at 1:1000 dilution.
