ARG63753
anti-DYX1C1 / EKN1 antibody
anti-DYX1C1 / EKN1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Controls and Markers antibody; Neuroscience antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes DYX1C1 / EKN1 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat |
| Tested Application | IHC-P, WB |
| Specificity | This antibody is expected to recognise only one of the three reported isoforms (NP_570722.2, isoform a). |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | DYX1C1 / EKN1 |
| Antigen Species | Human |
| Immunogen | C-KIRNVIQGTELKS |
| Conjugation | Un-conjugated |
| Alternate Names | DYX1; CILD25; Dyslexia susceptibility 1 candidate gene 1 protein; RD; EKN1; DYXC1; DNAAF4 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8WXU2 Human Dyslexia susceptibility 1 candidate gene 1 protein |
|---|---|
| Background | This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. An homologous protein in rat has been shown to function in neuronal migration in the developing neocortex. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream cell cycle progression 1 (CCPG1) gene. [provided by RefSeq, Mar 2011] |
| Research Area | Controls and Markers antibody; Neuroscience antibody |
| Calculated MW | 49 kDa |
Images (1) Click the Picture to Zoom In
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ARG63753 anti-DYX1C1 / EKN1 antibody IHC-P image
Immunohistochemistry: Paraffin embedded Human Cerebral Cortex. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63753 anti-DYX1C1 / EKN1 antibody at 5 µg/ml dilution followed by AP-staining.
