ARG67093
anti-DSPP antibody
anti-DSPP antibody for ICC/IF,Western blot and
Overview
| Product Description | Rabbit Polyclonal antibody recognizes DSPP |
|---|---|
| Predict Reactivity | Hu |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | DSPP |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human DSPP |
| Conjugation | Un-conjugated |
| Protein Full Name | Dentin sialophosphoprotein |
| Alternate Names | DSPP; Dentin Sialophosphoprotein; DMP3; DFNA39; DGI1; Deafness, Autosomal Dominant 39; Dentin Phosphoprotein; Dentin Phosphophoryn; Dentin Sialoprotein; Dentin Phosphoryn; DPP; DSP |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 110 ~120 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 30% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | DSPP |
|---|---|
| Gene Full Name | Dentin Sialophosphoprotein |
| Background | This gene encodes a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family of proteins. The encoded preproprotein is secreted by odontoblasts and proteolytically processed to generate two principal proteins of the dentin extracellular matrix of the tooth, dentin sialoprotein and dentin phosphoprotein. These two protein products may play distinct but related roles in dentin mineralization. Mutations in this gene are associated with dentinogenesis imperfecta and dentin dysplasia. This gene is present in a gene cluster on chromosome 4. Allelic differences due to repeat polymorphisms have been found for this gene. |
| Function | DSP may be an important factor in dentinogenesis. DPP may bind high amount of calcium and facilitate initial mineralization of dentin matrix collagen as well as regulate the size and shape of the crystals. |
| Cellular Localization | Extracellular matrix, Secreted |
| Calculated MW | 131 kDa |
| PTM | Glycoprotein, Phosphoprotein |
Images (2) Click the Picture to Zoom In
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ARG67093 anti-DSPP antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG67093 anti-DSPP antibody.
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ARG67093 anti-DSPP antibody WB image
Western blot: MCF7 and HL60 stained with ARG67093 anti-DSPP antibody.
