ARG65023
anti-DSG1 / Desmoglein 1 antibody
anti-DSG1 / Desmoglein 1 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes DSG1 / Desmoglein 1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | DSG1 / Desmoglein 1 |
| Antigen Species | Human |
| Immunogen | C-YTTSDTLKPSVHVHD |
| Conjugation | Un-conjugated |
| Alternate Names | PPKS1; Desmoglein-1; SPPK1; DGI; EPKHIA; CDHF4; DG1; Desmosomal glycoprotein 1; DSG; Cadherin family member 4; Pemphigus foliaceus antigen; EPKHE |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus. [provided by RefSeq, Jul 2008] |
| Research Area | Signaling Transduction antibody |
| Calculated MW | 114 kDa |
Images (1) Click the Picture to Zoom In
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ARG65023 anti-DSG1 / Desmoglein 1 antibody IHC-P image
Immunohistochemistry: Paraffin embedded Human Skin. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG65023 anti-DSG1 / Desmoglein 1 antibody at 3.8 µg/ml dilution followed by AP-staining.
