ARG43835
anti-DLST antibody
anti-DLST antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes DLST. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Dihydrolipoamide S-Succinyltransferase |
| Immunogen | Recombinant fragment of human DLST (aa.188 - 453). |
| Conjugation | Un-conjugated |
| Alternate Names | DLST; Dihydrolipoamide S-Succinyltransferase; OGDC-E2; KGD2; DLTS; Dihydrolipoyllysine-Residue Succinyltransferase Component Of 2-Oxoglutarate Dehydrogenase Complex, Mitochondrial; Dihydrolipoamide S-Succinyltransferase (E2 Component Of 2-Oxo-Glutarate Complex); 2-Oxoglutarate Dehydrogenase Complex Component E2; EC 2.3.1.61; E2K; Dihydrolipoamide Succinyltransferase Component Of 2-Oxoglutarate Dehydrogenase Complex; Dihydrolipoyllysine-Residue Succinyltransferase; EC 2.3.1; PGL7 |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | Tris-Glycine (pH 7) with 0.01% Thimerosal |
| Preservative | 0.01% Thimerosal |
| Concentration | 700 µg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P36957 Human Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarat |
|---|---|
| Gene Symbol | DLST |
| Gene Full Name | Dihydrolipoamide S-Succinyltransferase |
| Background | This gene encodes a mitochondrial protein that belongs to the 2-oxoacid dehydrogenase family. This protein is one of the three components (the E2 component) of the 2-oxoglutarate dehydrogenase complex that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011] |
| Function | A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A. |
| Cellular Localization | Mitochondrion, Nucleus |
| PTM | Acetylation, Phosphoprotein |
Images (3) Click the Picture to Zoom In
-
ARG43835 anti-DLST antibody IHC-P image
Immunohistochemistry: Human carcinoma stained with ARG43835 anti-DLST antibody at 1:500 dilution.
-
ARG43835 anti-DLST antibody WB image
Western blot: A431 stained with ARG43835 anti-DLST antibody at 1:1000 dilution.
-
ARG43835 anti-DLST antibody ICC/IF image
Immunofluorescence: A431 cells stained with ARG43835 anti-DLST antibody at 1:500 dilution.
